Lunesta Abuse

Lunesta Eszopiclone is a nonbenzodiazepine hypnotic agent used as a medication in treatment of insomnia. Eszopiclone is the active stereoisomer of zopiclone. Eszopiclone is a white to light-yellow crystalline solid. It is very lightly soluble in water, slightly soluble in ethanol and soluble in phosphate buffer (pH 3.2). The precise mechanism of action of eszopiclone as a hypnotic is unknown, but its effect is believed to result from its interaction with GABA receptor complexes at bindings domains located close to or allosterically coupled to benzodiazepine receptors. Approved by the Food and Drug Administration for sale in the United States in 2005, eszoplicone is sold by the pharmaceutical company Sepracor under the name Lunesta. Unlike the leading prescription sleep aid zolpidem (Ambien), eszopiclone is approved by the FDA for use longer than two weeks. Trials suggest that patients do not get addicted to Lunesta.
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